BDBM158944 US9034866, 419

SMILES: CNC(=O)c1c(nc2-c3cc(ccc3OCCn12)C#C[C@]1(O)CCN(C)C1=O)C(N)=O

InChI Key: InChIKey=LCMHUDOMYXMPFH-NRFANRHFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human))	BDBM158944 (US9034866, 419) Show SMILES CNC(=O)c1c(nc2-c3cc(ccc3OCCn12)C#C[C@]1(O)CCN(C)C1=O)C(N)=O |r| Show InChI InChI=1S/C21H21N5O5/c1-23-19(28)16-15(17(22)27)24-18-13-11-12(3-4-14(13)31-10-9-26(16)18)5-6-21(30)7-8-25(2)20(21)29/h3-4,11,30H,7-10H2,1-2H3,(H2,22,27)(H,23,28)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Genentech, Inc. US Patent					Assay Description The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...				US Patent US9034866 (2015) BindingDB Entry DOI: 10.7270/Q2GX49B0
					More data for this Ligand-Target Pair