BDBM159240 US9034866, 717

SMILES: CN1CC[C@@](O)(C#Cc2ccc3OCC4(CCC4)c4cc(nn4-c3c2)C(N)=O)C1=O

InChI Key: InChIKey=MHYLKDTZNSASFI-QFIPXVFZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human))	BDBM159240 (US9034866, 717) Show SMILES CN1CC[C@@](O)(C#Cc2ccc3OCC4(CCC4)c4cc(nn4-c3c2)C(N)=O)C1=O |r| Show InChI InChI=1S/C22H22N4O4/c1-25-10-9-22(29,20(25)28)8-5-14-3-4-17-16(11-14)26-18(12-15(24-26)19(23)27)21(13-30-17)6-2-7-21/h3-4,11-12,29H,2,6-7,9-10,13H2,1H3,(H2,23,27)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Genentech, Inc. US Patent					Assay Description The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...				US Patent US9034866 (2015) BindingDB Entry DOI: 10.7270/Q2GX49B0
					More data for this Ligand-Target Pair