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SMILES: Cc1cc(CN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(CCCC3CCCC3)cc2F)c(C)n1-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=NALUHFIXAFGMBH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159659   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
2-acylglycerol O-acyltransferase 2


(Homo sapiens (Human))		BDBM159659
PNG
(US9035059, 7-81)
Show SMILES Cc1cc(CN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(CCCC3CCCC3)cc2F)c(C)n1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C37H41F4N3O2S/c1-25-19-31(26(2)44(25)33-12-6-11-32(22-33)37(39,40)41)24-43-18-17-29-21-34(15-14-30(29)23-43)47(45,46)42-36-16-13-28(20-35(36)38)10-5-9-27-7-3-4-8-27/h6,11-16,19-22,27,42H,3-5,7-10,17-18,23-24H2,1-2H3
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antibodypedia
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Similars
US Patent
n/an/a 45n/an/an/an/an/a25



TAISHO PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...

US Patent US9035059 (2015)


BindingDB Entry DOI: 10.7270/Q2B856WH
More data for this
Ligand-Target Pair