BDBM159792 US9040501, 878895

SMILES: OC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)N1CC=CCNC1=O

InChI Key: InChIKey=FHJRJJBDJACZGH-BZNPZCIMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytidine deaminase (CDA) (Homo sapiens (Human))	BDBM159792 (US9040501, 878895) Show SMILES OC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)N1CC=CCNC1=O |r,c:12| Show InChI InChI=1S/C10H15FN2O4/c11-7-8(15)6(5-14)17-9(7)13-4-2-1-3-12-10(13)16/h1-2,6-9,14-15H,3-5H2,(H,12,16)/t6-,7+,8-,9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	7.4	n/a
Otsuka Pharmaceutical Co., Ltd. US Patent					Assay Description The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....				US Patent US9040501 (2015) BindingDB Entry DOI: 10.7270/Q22R3QD1
					More data for this Ligand-Target Pair