BDBM160217 US9040663, 63
SMILES: C[C@@H](OCc1ccccc1)[C@@H]1NC(=O)[C@H](CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2Cl)NC1=O)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O
InChI Key:
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM160217 (US9040663, 63) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.350 | -13.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
AstraZeneca AB US Patent | Assay Description A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK... | US Patent US9040663 (2015) BindingDB Entry DOI: 10.7270/Q29885SK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM160217 (US9040663, 63) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 12 | -11.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
AstraZeneca AB US Patent | Assay Description A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK... | US Patent US9040663 (2015) BindingDB Entry DOI: 10.7270/Q29885SK | |||||||||||
More data for this Ligand-Target Pair |