null

SMILES: OC(=O)c1scc2[nH]c(=O)n(-c3cc(ccc3Cl)S(=O)(=O)N3CCCc4ccccc34)c(=O)c12

InChI Key: InChIKey=OAPXLIYGMXPBRL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160321   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM160321 (US9040693, 22) Show SMILES OC(=O)c1scc2[nH]c(=O)n(-c3cc(ccc3Cl)S(=O)(=O)N3CCCc4ccccc34)c(=O)c12 |(-8.56,-1.78,;-7.02,-1.78,;-6.25,-3.11,;-6.25,-.44,;-7.15,.8,;-6.25,2.05,;-4.78,1.57,;-3.45,2.34,;-2.11,1.57,;-.78,2.34,;-2.11,.03,;-.78,-.74,;.55,.03,;1.89,-.74,;1.89,-2.28,;.55,-3.05,;-.78,-2.28,;-2.11,-3.05,;3.22,.03,;2.45,1.37,;3.99,-1.3,;4.55,.8,;4.55,2.34,;5.89,3.11,;7.22,2.34,;7.22,.8,;8.56,.03,;8.56,-1.51,;7.22,-2.28,;5.89,-1.51,;5.89,.03,;-3.45,-.74,;-3.45,-2.28,;-4.78,.03,)| Show InChI InChI=1S/C22H16ClN3O6S2/c23-14-8-7-13(34(31,32)25-9-3-5-12-4-1-2-6-16(12)25)10-17(14)26-20(27)18-15(24-22(26)30)11-33-19(18)21(28)29/h1-2,4,6-8,10-11H,3,5,9H2,(H,24,30)(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
KISSEI PHARMACEUTICAL CO., LTD. US Patent					Assay Description Antagonizing effect of compounds for human GnRHR1 was evaluated by change of calcium levels in GnRH-stimulated cells. After removing the culture medi...				US Patent US9040693 (2015) BindingDB Entry DOI: 10.7270/Q21R6P8N
					More data for this Ligand-Target Pair