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BDBM160488 US10093663, Example 29::US9682968, Example-29

SMILES: COC1CCC(N(Cc2c(OC)cc(C)c3[nH]ccc23)C1)c1ccc(cc1)C(N)=O

InChI Key:

Data: 2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 160488
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Complement factor B (Homo sapiens (Human))	BDBM160488 (US10093663, Example 29 \| US9682968, Example-29) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US10093663 (2018) BindingDB Entry DOI: 10.7270/Q2DF6T75
Novartis AG US Patent					More data for this Ligand-Target Pair
Complement factor B (Homo sapiens (Human))	BDBM160488 (US10093663, Example 29 \| US9682968, Example-29) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US9682968 (2017) BindingDB Entry DOI: 10.7270/Q2XG9P9J
Novartis AG US Patent					More data for this Ligand-Target Pair