BindingDB logo
myBDB logout

null

SMILES: NCC(Cc1ccccc1)c1ccc2CCN(Cc2c1)S(=O)(=O)CC1CC1

InChI Key: InChIKey=VQFROBTWUQSFMY-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160586   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))		BDBM160586
PNG
(US9045459, 3)
Show SMILES NCC(Cc1ccccc1)c1ccc2CCN(Cc2c1)S(=O)(=O)CC1CC1
Show InChI InChI=1S/C22H28N2O2S/c23-14-21(12-17-4-2-1-3-5-17)20-9-8-19-10-11-24(15-22(19)13-20)27(25,26)16-18-6-7-18/h1-5,8-9,13,18,21H,6-7,10-12,14-16,23H2
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<1.00E+4n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...

US Patent US9045459 (2015)


BindingDB Entry DOI: 10.7270/Q28914M9
More data for this
Ligand-Target Pair