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SMILES: FC(F)Oc1c(F)cc(F)cc1C1CCN(CC1)c1cnn2c(CC3CC3)nnc2c1Cl

InChI Key: InChIKey=XTFRCEYEJFYGMW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160776   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM160776
PNG
(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(2-...)
Show SMILES FC(F)Oc1c(F)cc(F)cc1C1CCN(CC1)c1cnn2c(CC3CC3)nnc2c1Cl
Show InChI InChI=1S/C21H20ClF4N5O/c22-18-16(10-27-31-17(7-11-1-2-11)28-29-20(18)31)30-5-3-12(4-6-30)14-8-13(23)9-15(24)19(14)32-21(25)26/h8-12,21H,1-7H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 10n/an/a7.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...

US Patent US9682980 (2017)


BindingDB Entry DOI: 10.7270/Q2J964JS
More data for this
Ligand-Target Pair