BDBM160975 US9108903, 40
SMILES: OCc1ccc(Oc2cc(Cl)c(Cl)cc2C(=O)Nc2ccc(nc2)C(O)=O)cc1F
InChI Key: InChIKey=JDJWKYYLBOHSSI-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 10 subunit alpha (Rattus norvegicus (Rat)) | BDBM160975 (US9108903, 40) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
VERTEX PHARMACEUTICALS INCORPORATED US Patent | Assay Description Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons... | US Patent US9108903 (2015) BindingDB Entry DOI: 10.7270/Q23J3BP9 | |||||||||||
More data for this Ligand-Target Pair |