BDBM16101 3-carbamoyl-5-[3-(4-methylphenyl)phenyl]benzoic acid::5-carbamoyl-4 -methyl-1,1 :3 ,1 -terphenyl-3-carboxylic acid::AMX07::Brequinar-derived asymmetric terphenyl compound

SMILES: Cc1ccc(cc1)-c1cccc(c1)-c1cc(cc(c1)C(O)=O)C(N)=O

InChI Key: InChIKey=RYSLAQISVNDTBT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM16101 (3-carbamoyl-5-[3-(4-methylphenyl)phenyl]benzoic ac...) Show SMILES Cc1ccc(cc1)-c1cccc(c1)-c1cc(cc(c1)C(O)=O)C(N)=O Show InChI InChI=1S/C21H17NO3/c1-13-5-7-14(8-6-13)15-3-2-4-16(9-15)17-10-18(20(22)23)12-19(11-17)21(24)25/h2-12H,1H3,(H2,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	-7.28	n/a	n/a	n/a	n/a	n/a	8.0	22
Cornell University					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 1610-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.029 BindingDB Entry DOI: 10.7270/Q2H993FV
					More data for this Ligand-Target Pair