BDBM161175 US9682976, 61

SMILES: CC1(C)C[C@H](C[C@H]2CCCN12)Nc1nc(Nc2ccc(O[C@@H]3CCOC3)c(c2)C#N)ncc1F

InChI Key: InChIKey=OTPWEBUGLWNXLO-XUVXKRRUSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (Homo sapiens (Human))	BDBM161175 (US9682976, 61) Show SMILES CC1(C)C[C@H](C[C@H]2CCCN12)Nc1nc(Nc2ccc(O[C@@H]3CCOC3)c(c2)C#N)ncc1F |r| Show InChI InChI=1S/C25H31FN6O2/c1-25(2)12-18(11-19-4-3-8-32(19)25)29-23-21(26)14-28-24(31-23)30-17-5-6-22(16(10-17)13-27)34-20-7-9-33-15-20/h5-6,10,14,18-20H,3-4,7-9,11-12,15H2,1-2H3,(H2,28,29,30,31)/t18-,19+,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
Rigel Pharmaceuticals, Inc. US Patent					Assay Description Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...				US Patent US9682976 (2017) BindingDB Entry DOI: 10.7270/Q2DJ5CT2
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