BDBM161404 US10124003, Ex. Compound 17::US10835536, Ex. Comp 17::US10894048, Ex Comp 17::US9108973, 17

SMILES: CCN(CC)C\C=C\C(=O)N1CC(C1)n1nc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12

InChI Key: InChIKey=UJFBAHIADKKHCM-BQYQJAHWSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 161404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161404 (US10124003, Ex. Compound 17 | US10835536, Ex. Comp...) Show SMILES CCN(CC)C\C=C\C(=O)N1CC(C1)n1nc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C26H31N7O3/c1-5-31(6-2)11-7-8-23(34)32-15-19(16-32)33-26-24(25(27)28-17-29-26)22(30-33)10-9-18-12-20(35-3)14-21(13-18)36-4/h7-8,12-14,17,19H,5-6,11,15-16H2,1-4H3,(H2,27,28,29)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	7.5	25
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161404 (US10124003, Ex. Compound 17 | US10835536, Ex. Comp...) Show SMILES CCN(CC)C\C=C\C(=O)N1CC(C1)n1nc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C26H31N7O3/c1-5-31(6-2)11-7-8-23(34)32-15-19(16-32)33-26-24(25(27)28-17-29-26)22(30-33)10-9-18-12-20(35-3)14-21(13-18)36-4/h7-8,12-14,17,19H,5-6,11,15-16H2,1-4H3,(H2,27,28,29)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10894048 (2021)
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161404 (US10124003, Ex. Compound 17 | US10835536, Ex. Comp...) Show SMILES CCN(CC)C\C=C\C(=O)N1CC(C1)n1nc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C26H31N7O3/c1-5-31(6-2)11-7-8-23(34)32-15-19(16-32)33-26-24(25(27)28-17-29-26)22(30-33)10-9-18-12-20(35-3)14-21(13-18)36-4/h7-8,12-14,17,19H,5-6,11,15-16H2,1-4H3,(H2,27,28,29)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10835536 (2020)
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161404 (US10124003, Ex. Compound 17 | US10835536, Ex. Comp...) Show SMILES CCN(CC)C\C=C\C(=O)N1CC(C1)n1nc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C26H31N7O3/c1-5-31(6-2)11-7-8-23(34)32-15-19(16-32)33-26-24(25(27)28-17-29-26)22(30-33)10-9-18-12-20(35-3)14-21(13-18)36-4/h7-8,12-14,17,19H,5-6,11,15-16H2,1-4H3,(H2,27,28,29)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10124003 (2018) BindingDB Entry DOI: 10.7270/Q2B27XBQ
					More data for this Ligand-Target Pair