BDBM161455 US9108973, 68

SMILES: COc1cc(OC)cc(c1)C#Cc1cn([C@H]2C[C@H](N(C2)C(=O)C=C)c2nnco2)c2ncnc(N)c12

InChI Key: InChIKey=WISXJFMZEPSSAV-PXNSSMCTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161455 (US9108973, 68) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2C[C@H](N(C2)C(=O)C=C)c2nnco2)c2ncnc(N)c12 |r| Show InChI InChI=1S/C25H23N7O4/c1-4-21(33)32-12-17(9-20(32)25-30-29-14-36-25)31-11-16(22-23(26)27-13-28-24(22)31)6-5-15-7-18(34-2)10-19(8-15)35-3/h4,7-8,10-11,13-14,17,20H,1,9,12H2,2-3H3,(H2,26,27,28)/t17-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	25
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV
					More data for this Ligand-Target Pair