BDBM161985 US9682991, 34

SMILES: CN(C)c1cccc(c1)-c1nnc2c3OCCN(C)c3c(NCC3CCN(C)CC3)nn12

InChI Key: InChIKey=CXINRXVREHWMLQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 161985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161985 (US9682991, 34) Show SMILES CN(C)c1cccc(c1)-c1nnc2c3OCCN(C)c3c(NCC3CCN(C)CC3)nn12 Show InChI InChI=1S/C23H32N8O/c1-28(2)18-7-5-6-17(14-18)22-25-26-23-20-19(30(4)12-13-32-20)21(27-31(22)23)24-15-16-8-10-29(3)11-9-16/h5-7,14,16H,8-13,15H2,1-4H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161985 (US9682991, 34) Show SMILES CN(C)c1cccc(c1)-c1nnc2c3OCCN(C)c3c(NCC3CCN(C)CC3)nn12 Show InChI InChI=1S/C23H32N8O/c1-28(2)18-7-5-6-17(14-18)22-25-26-23-20-19(30(4)12-13-32-20)21(27-31(22)23)24-15-16-8-10-29(3)11-9-16/h5-7,14,16H,8-13,15H2,1-4H3,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM161985 (US9682991, 34) Show SMILES CN(C)c1cccc(c1)-c1nnc2c3OCCN(C)c3c(NCC3CCN(C)CC3)nn12 Show InChI InChI=1S/C23H32N8O/c1-28(2)18-7-5-6-17(14-18)22-25-26-23-20-19(30(4)12-13-32-20)21(27-31(22)23)24-15-16-8-10-29(3)11-9-16/h5-7,14,16H,8-13,15H2,1-4H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-2 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair