BDBM16231 2-(4-chlorophenyl)-N-methyl-2-[4-(9H-purin-6-yl)phenyl]ethanamine::6-phenylpurine compound 18::[2-(4-chlorophenyl)-2-[4-(9H-purin-6-yl)phenyl]ethyl](methyl)amine

SMILES: CNCC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ncnc2nc[nH]c12

InChI Key: InChIKey=IPHKZGAEKMFMAW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM16231 (2-(4-chlorophenyl)-N-methyl-2-[4-(9H-purin-6-yl)ph...) Show SMILES CNCC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ncnc2nc[nH]c12 Show InChI InChI=1S/C20H18ClN5/c1-22-10-17(14-6-8-16(21)9-7-14)13-2-4-15(5-3-13)18-19-20(25-11-23-18)26-12-24-19/h2-9,11-12,17,22H,10H2,1H3,(H,23,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.2	22
Astex					Assay Description The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...				J Med Chem 50: 2289-92 (2007) Article DOI: 10.1021/jm0700924 BindingDB Entry DOI: 10.7270/Q2M32T1C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM16231 (2-(4-chlorophenyl)-N-methyl-2-[4-(9H-purin-6-yl)ph...) Show SMILES CNCC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ncnc2nc[nH]c12 Show InChI InChI=1S/C20H18ClN5/c1-22-10-17(14-6-8-16(21)9-7-14)13-2-4-15(5-3-13)18-19-20(25-11-23-18)26-12-24-19/h2-9,11-12,17,22H,10H2,1H3,(H,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.2	22
Astex					Assay Description The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...				J Med Chem 50: 2289-92 (2007) Article DOI: 10.1021/jm0700924 BindingDB Entry DOI: 10.7270/Q2M32T1C
					More data for this Ligand-Target Pair