BDBM162874 US9056859, 122

SMILES: Cc1c(CCN2CCN(CC2)C(=O)Cc2ccc(cc2)-n2cnnn2)ccc(F)c1[N+]#[C-]

InChI Key: InChIKey=LVUBRMJZLGDVHQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162874   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Rattus norvegicus (Rat))	BDBM162874 (US9056859, 122) Show SMILES Cc1c(CCN2CCN(CC2)C(=O)Cc2ccc(cc2)-n2cnnn2)ccc(F)c1[N+]#[C-] Show InChI InChI=1S/C23H24FN7O/c1-17-19(5-8-21(24)23(17)25-2)9-10-29-11-13-30(14-12-29)22(32)15-18-3-6-20(7-4-18)31-16-26-27-28-31/h3-8,16H,9-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9056859 (2015) BindingDB Entry DOI: 10.7270/Q20P0XS0
					More data for this Ligand-Target Pair