BDBM162875 US9056859, 177

SMILES: C[C@H]1Cc2cc(CCN3CCN(CC3)C(=O)C3CCc4nc(ccc34)-n3cnnn3)ccc2C(=O)O1

InChI Key: InChIKey=USJYUQVZKANXEJ-LBOXEOMUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renal Outer Medullary Potassium (ROMK) (Rattus norvegicus (Rat))	BDBM162875 (US9056859, 177) Show SMILES C[C@H]1Cc2cc(CCN3CCN(CC3)C(=O)C3CCc4nc(ccc34)-n3cnnn3)ccc2C(=O)O1 |r| Show InChI InChI=1S/C26H29N7O3/c1-17-14-19-15-18(2-3-20(19)26(35)36-17)8-9-31-10-12-32(13-11-31)25(34)22-4-6-23-21(22)5-7-24(28-23)33-16-27-29-30-33/h2-3,5,7,15-17,22H,4,6,8-14H2,1H3/t17-,22?/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...				US Patent US9056859 (2015) BindingDB Entry DOI: 10.7270/Q20P0XS0
					More data for this Ligand-Target Pair