BDBM163212 US9062045, 52

SMILES: Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc(NC5CCOC5)cc4c3)n2c1

InChI Key: InChIKey=BNUGVTQOMSYBMV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM163212 (US9062045, 52) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc(NC5CCOC5)cc4c3)n2c1 Show InChI InChI=1S/C23H20FN7OS/c1-30-11-16(9-26-30)15-8-20(24)22-28-29-23(31(22)12-15)33-19-2-3-21-14(7-19)6-18(10-25-21)27-17-4-5-32-13-17/h2-3,6-12,17,27H,4-5,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-F...				US Patent US9062045 (2015) BindingDB Entry DOI: 10.7270/Q23F4NDS
					More data for this Ligand-Target Pair