BDBM163224 US9062045, 67

SMILES: Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc(cc4c3)N3CCC(F)(F)CC3)n2c1

InChI Key: InChIKey=IABXEOYJCXGIMD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM163224 (US9062045, 67) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc(cc4c3)N3CCC(F)(F)CC3)n2c1 Show InChI InChI=1S/C24H20F3N7S/c1-32-13-17(11-29-32)16-10-20(25)22-30-31-23(34(22)14-16)35-19-2-3-21-15(9-19)8-18(12-28-21)33-6-4-24(26,27)5-7-33/h2-3,8-14H,4-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-F...				US Patent US9062045 (2015) BindingDB Entry DOI: 10.7270/Q23F4NDS
					More data for this Ligand-Target Pair