BDBM163691 1‐(4‐Methoxy‐2,5‐dimethylbenzenesulfonyl)‐4‐methyl‐2‐phenylimidazole (0105)

SMILES: COc1cc(C)c(cc1C)S(=O)(=O)n1cc(C)nc1-c1ccccc1

InChI Key: InChIKey=IOSRESPDILIUNP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
8-Oxoguanine DNA glycosylase-1 (OGG1) (Homo sapiens (Human))	BDBM163691 (1‐(4‐Methoxy‐2,5‐dimethylb...) Show SMILES COc1cc(C)c(cc1C)S(=O)(=O)n1cc(C)nc1-c1ccccc1 Show InChI InChI=1S/C19H20N2O3S/c1-13-11-18(14(2)10-17(13)24-4)25(22,23)21-12-15(3)20-19(21)16-8-6-5-7-9-16/h5-12H,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.15E+3	n/a	n/a	n/a	n/a	7.5	37
Oregon Health & Science University					Assay Description A total of 4 µL of OGG1 (125 nM) was mixed with 1 µL of inhibitor. In a separate tube, 1 µL of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi...				ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H
					More data for this Ligand-Target Pair