BDBM163707 Cyclo L-OH-Pro-L-Phe (Fr. 1-4)

SMILES: O[C@@H]1C[C@@H]2N(C1)C(=O)[C@H](Cc1ccccc1)NC2=O

InChI Key: InChIKey=PYQJYHACQOBZLF-WOPDTQHZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM163707 (Cyclo L-OH-Pro-L-Phe (Fr. 1-4)) Show SMILES O[C@@H]1C[C@@H]2N(C1)C(=O)[C@H](Cc1ccccc1)NC2=O |r| Show InChI InChI=1S/C14H16N2O3/c17-10-7-12-13(18)15-11(14(19)16(12)8-10)6-9-4-2-1-3-5-9/h1-5,10-12,17H,6-8H2,(H,15,18)/t10-,11+,12+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	773	n/a	n/a	n/a	n/a	8.0	n/a
Chinese Academy of Sciences					Assay Description Recombinant human DHODH (final enzyme concentration between 20 and 60 nM in the assay well) were incubated at 37 °C in 50 mM Tris-HCl, 0.1% Triton X-...				Chem Biol Drug Des 86: 626-36 (2015) Article DOI: 10.1111/cbdd.12530 BindingDB Entry DOI: 10.7270/Q2JH3JXM
					More data for this Ligand-Target Pair