null

SMILES: NCC(=O)N1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1

InChI Key: InChIKey=UDTCECNLYWXABA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 164201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM164201 (US9688615, 12) Show SMILES NCC(=O)N1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1 Show InChI InChI=1S/C15H14F6N4O/c16-14(17,18)8-2-9(15(19,20)21)13-10(3-8)23-11(24-13)1-7-5-25(6-7)12(26)4-22/h2-3,7H,1,4-6,22H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...				US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM164201 (US9688615, 12) Show SMILES NCC(=O)N1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1 Show InChI InChI=1S/C15H14F6N4O/c16-14(17,18)8-2-9(15(19,20)21)13-10(3-8)23-11(24-13)1-7-5-25(6-7)12(26)4-22/h2-3,7H,1,4-6,22H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...				US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human))	BDBM164201 (US9688615, 12) Show SMILES NCC(=O)N1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1 Show InChI InChI=1S/C15H14F6N4O/c16-14(17,18)8-2-9(15(19,20)21)13-10(3-8)23-11(24-13)1-7-5-25(6-7)12(26)4-22/h2-3,7H,1,4-6,22H2,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...				US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM164201 (US9688615, 12) Show SMILES NCC(=O)N1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1 Show InChI InChI=1S/C15H14F6N4O/c16-14(17,18)8-2-9(15(19,20)21)13-10(3-8)23-11(24-13)1-7-5-25(6-7)12(26)4-22/h2-3,7H,1,4-6,22H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
SRMLSC US Patent					Assay Description To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...				US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM164201 (US9688615, 12) Show SMILES NCC(=O)N1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1 Show InChI InChI=1S/C15H14F6N4O/c16-14(17,18)8-2-9(15(19,20)21)13-10(3-8)23-11(24-13)1-7-5-25(6-7)12(26)4-22/h2-3,7H,1,4-6,22H2,(H,23,24)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...				US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM164201 (US9688615, 12) Show SMILES NCC(=O)N1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1 Show InChI InChI=1S/C15H14F6N4O/c16-14(17,18)8-2-9(15(19,20)21)13-10(3-8)23-11(24-13)1-7-5-25(6-7)12(26)4-22/h2-3,7H,1,4-6,22H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
SRMLSC US Patent					Assay Description To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...				US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM164201 (US9688615, 12) Show SMILES NCC(=O)N1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1 Show InChI InChI=1S/C15H14F6N4O/c16-14(17,18)8-2-9(15(19,20)21)13-10(3-8)23-11(24-13)1-7-5-25(6-7)12(26)4-22/h2-3,7H,1,4-6,22H2,(H,23,24)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...				US Patent US9688615 (2017) BindingDB Entry DOI: 10.7270/Q27S7KXH
					More data for this Ligand-Target Pair