BDBM164388 US9669029, 91 8-Methoxy-5-methyl-2-[2-(1-methyl-4-thiazol-5-yl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyridine

SMILES: COC1=CC=C(C)N2N=C(CCc3nc(cn3C)-c3cncs3)NC12

InChI Key: InChIKey=BMNMVQTVBQYPRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PED10A (Homo sapiens (Human))	BDBM164388 (US9669029, 91 8-Methoxy-5-methyl-2-[2-(1-methyl-4-...) Show SMILES COC1=CC=C(C)N2N=C(CCc3nc(cn3C)-c3cncs3)NC12 |t:2,4,8| Show InChI InChI=1S/C17H20N6OS/c1-11-4-5-13(24-3)17-20-15(21-23(11)17)6-7-16-19-12(9-22(16)2)14-8-18-10-25-14/h4-5,8-10,17H,6-7H2,1-3H3,(H,20,21)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	25
TBA US Patent					Assay Description The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...				US Patent US9669029 (2017) BindingDB Entry DOI: 10.7270/Q2BG2M4J
					More data for this Ligand-Target Pair