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SMILES: Oc1ccc(Cc2nnc3ccc(cn23)-c2ccccn2)cc1

InChI Key: InChIKey=GKFDTBCRONOGCP-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164425   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM164425
PNG
(US9066954, 67)
Show SMILES Oc1ccc(Cc2nnc3ccc(cn23)-c2ccccn2)cc1
Show InChI InChI=1S/C18H14N4O/c23-15-7-4-13(5-8-15)11-18-21-20-17-9-6-14(12-22(17)18)16-3-1-2-10-19-16/h1-10,12,23H,11H2
PDB
MMDB

KEGG

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PC cid
PC sid
UniChem

Similars

US Patent
758 -8.40n/an/an/an/an/a8.027



Amgen Inc.

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...


US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair