BDBM164430 US9066954, 75

SMILES: CNC(=O)c1ccc(s1)-c1ccc2nnc(COc3ccnc4cc(OC)ccc34)n2c1

InChI Key: InChIKey=CSMXLLRMUADVMZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164430 (US9066954, 75) Show SMILES CNC(=O)c1ccc(s1)-c1ccc2nnc(COc3ccnc4cc(OC)ccc34)n2c1 Show InChI InChI=1S/C23H19N5O3S/c1-24-23(29)20-7-6-19(32-20)14-3-8-21-26-27-22(28(21)12-14)13-31-18-9-10-25-17-11-15(30-2)4-5-16(17)18/h3-12H,13H2,1-2H3,(H,24,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.20	-11.9	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair