BindingDB logo
myBDB logout

null

SMILES: COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc(=O)n(C)c3)ccnc2c1

InChI Key: InChIKey=KOTOUGDLBUEWTE-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164454   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM164454
PNG
(US9066954, 186)
Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc(=O)n(C)c3)ccnc2c1
Show InChI InChI=1S/C22H18N6O3/c1-27-12-14(3-8-22(27)29)17-6-7-20-24-25-21(28(20)26-17)13-31-19-9-10-23-18-11-15(30-2)4-5-16(18)19/h3-12H,13H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 6.20 -11.3n/an/an/an/an/a8.027



Amgen Inc.

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...

US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair