BDBM164460 US9066954, 209

SMILES: COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccncc3)ccnc2c1

InChI Key: InChIKey=LEKNFNRNFVAYOD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM164460 (US9066954, 209) Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccncc3)ccnc2c1 Show InChI InChI=1S/C21H16N6O2/c1-28-15-2-3-16-18(12-15)23-11-8-19(16)29-13-21-25-24-20-5-4-17(26-27(20)21)14-6-9-22-10-7-14/h2-12H,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.90	-11.0	n/a	n/a	n/a	n/a	n/a	8.0	27
Amgen Inc. US Patent					Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...				US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD
					More data for this Ligand-Target Pair