BDBM165103 US9067917, 138::US9682971, 138

SMILES: CS(=O)(=O)Nc1ccc(cc1)-c1cccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)c1

InChI Key: InChIKey=QCVADDPVWVPATF-OBOZPERJSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165103 (US9067917, 138 | US9682971, 138) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)c1 |r| Show InChI InChI=1S/C38H36N4O5S/c1-48(45,46)41-29-16-13-26(14-17-29)28-9-6-7-25(21-28)23-42-36-20-19-31(47-24-30-18-15-27-8-2-5-12-34(27)39-30)22-35(36)40-37(42)32-10-3-4-11-33(32)38(43)44/h2,5-9,12-22,32-33,41H,3-4,10-11,23-24H2,1H3,(H,43,44)/t32?,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165103 (US9067917, 138 | US9682971, 138) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)c1 |r| Show InChI InChI=1S/C38H36N4O5S/c1-48(45,46)41-29-16-13-26(14-17-29)28-9-6-7-25(21-28)23-42-36-20-19-31(47-24-30-18-15-27-8-2-5-12-34(27)39-30)22-35(36)40-37(42)32-10-3-4-11-33(32)38(43)44/h2,5-9,12-22,32-33,41H,3-4,10-11,23-24H2,1H3,(H,43,44)/t32?,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair