BDBM16515 2-(2-chlorophenyl)-6-[(2-methylphenyl)amino]-2,3-dihydropyridazin-3-one::2-arylpyridazin-3-one, 18

SMILES: Cc1ccccc1Nc1ccc(=O)n(n1)-c1ccccc1Cl

InChI Key: InChIKey=URYGFZDMQNLMKD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP Kinase p38 beta (Mus musculus (mouse))	BDBM16515 (2-(2-chlorophenyl)-6-[(2-methylphenyl)amino]-2,3-d...) Show SMILES Cc1ccccc1Nc1ccc(=O)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C17H14ClN3O/c1-12-6-2-4-8-14(12)19-16-10-11-17(22)21(20-16)15-9-5-3-7-13(15)18/h2-11H,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...				Bioorg Med Chem Lett 16: 5809-13 (2006) Article DOI: 10.1016/j.bmcl.2006.08.074 BindingDB Entry DOI: 10.7270/Q28P5XSC
					More data for this Ligand-Target Pair
MAP kinase p38 (Mus musculus (mouse))	BDBM16515 (2-(2-chlorophenyl)-6-[(2-methylphenyl)amino]-2,3-d...) Show SMILES Cc1ccccc1Nc1ccc(=O)n(n1)-c1ccccc1Cl Show InChI InChI=1S/C17H14ClN3O/c1-12-6-2-4-8-14(12)19-16-10-11-17(22)21(20-16)15-9-5-3-7-13(15)18/h2-11H,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	7.0	30
Merck Research Laboratories					Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...				Bioorg Med Chem Lett 16: 5809-13 (2006) Article DOI: 10.1016/j.bmcl.2006.08.074 BindingDB Entry DOI: 10.7270/Q28P5XSC
					More data for this Ligand-Target Pair