BDBM165153 US9067917, 188::US9682971, 188

SMILES: OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1)-c1ncccn1

InChI Key: InChIKey=MMKZKCWPBYLQQT-XIJSCUBXSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165153 (US9067917, 188 | US9682971, 188) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C35H31N5O3/c41-35(42)29-8-3-2-7-28(29)34-39-31-20-27(43-22-26-15-14-24-6-1-4-9-30(24)38-26)16-17-32(31)40(34)21-23-10-12-25(13-11-23)33-36-18-5-19-37-33/h1,4-6,9-20,28-29H,2-3,7-8,21-22H2,(H,41,42)/t28?,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165153 (US9067917, 188 | US9682971, 188) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C35H31N5O3/c41-35(42)29-8-3-2-7-28(29)34-39-31-20-27(43-22-26-15-14-24-6-1-4-9-30(24)38-26)16-17-32(31)40(34)21-23-10-12-25(13-11-23)33-36-18-5-19-37-33/h1,4-6,9-20,28-29H,2-3,7-8,21-22H2,(H,41,42)/t28?,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair