BDBM165164 US9067917, 199::US9682971, 199

SMILES: OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)N2CCCC2)CCCC1

InChI Key: InChIKey=NNXJRFSVHUPSBW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165164 (US9067917, 199 | US9682971, 199) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)N2CCCC2)CCCC1 Show InChI InChI=1S/C35H36N4O3/c40-34(41)35(16-3-4-17-35)22-33-37-31-21-29(42-24-27-13-12-26-9-1-2-11-30(26)36-27)14-15-32(31)39(33)23-25-8-7-10-28(20-25)38-18-5-6-19-38/h1-2,7-15,20-21H,3-6,16-19,22-24H2,(H,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM165164 (US9067917, 199 | US9682971, 199) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(c2)N2CCCC2)CCCC1 Show InChI InChI=1S/C35H36N4O3/c40-34(41)35(16-3-4-17-35)22-33-37-31-21-29(42-24-27-13-12-26-9-1-2-11-30(26)36-27)14-15-32(31)39(33)23-25-8-7-10-28(20-25)38-18-5-6-19-38/h1-2,7-15,20-21H,3-6,16-19,22-24H2,(H,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair