BDBM165207 US9062043, Table 10, Compound 10::US9062043, Table 13, Compound 1::US9062043, Table 20b, Compound 1

SMILES: OC(=O)c1ccc2c(c1)nc(Nc1ccccc1)c1ccncc21

InChI Key: InChIKey=KVQYHOITLPMKDW-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 165207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165207 (US9062043, Table 10, Compound 10 | US9062043, Tabl...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1ccccc1)c1ccncc21 Show InChI InChI=1S/C19H13N3O2/c23-19(24)12-6-7-14-16-11-20-9-8-15(16)18(22-17(14)10-12)21-13-4-2-1-3-5-13/h1-11H,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165207 (US9062043, Table 10, Compound 10 | US9062043, Tabl...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1ccccc1)c1ccncc21 Show InChI InChI=1S/C19H13N3O2/c23-19(24)12-6-7-14-16-11-20-9-8-15(16)18(22-17(14)10-12)21-13-4-2-1-3-5-13/h1-11H,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165207 (US9062043, Table 10, Compound 10 | US9062043, Tabl...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1ccccc1)c1ccncc21 Show InChI InChI=1S/C19H13N3O2/c23-19(24)12-6-7-14-16-11-20-9-8-15(16)18(22-17(14)10-12)21-13-4-2-1-3-5-13/h1-11H,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric filter-binding assay				J Med Chem 62: 1803-1816 (2019) Article DOI: 10.1021/acs.jmedchem.8b01766
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165207 (US9062043, Table 10, Compound 10 | US9062043, Tabl...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1ccccc1)c1ccncc21 Show InChI InChI=1S/C19H13N3O2/c23-19(24)12-6-7-14-16-11-20-9-8-15(16)18(22-17(14)10-12)21-13-4-2-1-3-5-13/h1-11H,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	7.4	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description The human leukemia Jurkat T-cell line was maintained in RPMI 1640 (Cambrex) supplemented with 10% fetal calf serum and 50 ng/ml Geutamycin. Before tr...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165207 (US9062043, Table 10, Compound 10 | US9062043, Tabl...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1ccccc1)c1ccncc21 Show InChI InChI=1S/C19H13N3O2/c23-19(24)12-6-7-14-16-11-20-9-8-15(16)18(22-17(14)10-12)21-13-4-2-1-3-5-13/h1-11H,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric filter-binding assay				J Med Chem 62: 1803-1816 (2019) Article DOI: 10.1021/acs.jmedchem.8b01766
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165207 (US9062043, Table 10, Compound 10 | US9062043, Tabl...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1ccccc1)c1ccncc21 Show InChI InChI=1S/C19H13N3O2/c23-19(24)12-6-7-14-16-11-20-9-8-15(16)18(22-17(14)10-12)21-13-4-2-1-3-5-13/h1-11H,(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair