BDBM16523 2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-trimethoxyphenyl)methyl]amino}propyl)amino]-2,3-dihydropyridazin-3-one::2-arylpyridazin-3-one, 29

SMILES: COc1ccc(CNCCCN(c2ccc(=O)n(n2)-c2ccccc2Cl)c2ccccc2Cl)c(OC)c1OC

InChI Key: InChIKey=OLFNUOKBBIASKG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP Kinase p38 beta (Mus musculus (mouse))	BDBM16523 (2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-...) Show SMILES COc1ccc(CNCCCN(c2ccc(=O)n(n2)-c2ccccc2Cl)c2ccccc2Cl)c(OC)c1OC Show InChI InChI=1S/C29H30Cl2N4O4/c1-37-25-14-13-20(28(38-2)29(25)39-3)19-32-17-8-18-34(23-11-6-4-9-21(23)30)26-15-16-27(36)35(33-26)24-12-7-5-10-22(24)31/h4-7,9-16,32H,8,17-19H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...				Bioorg Med Chem Lett 16: 5809-13 (2006) Article DOI: 10.1016/j.bmcl.2006.08.074 BindingDB Entry DOI: 10.7270/Q28P5XSC
					More data for this Ligand-Target Pair
MAP kinase p38 (Mus musculus (mouse))	BDBM16523 (2-(2-chlorophenyl)-6-[(2-chlorophenyl)(3-{[(2,3,4-...) Show SMILES COc1ccc(CNCCCN(c2ccc(=O)n(n2)-c2ccccc2Cl)c2ccccc2Cl)c(OC)c1OC Show InChI InChI=1S/C29H30Cl2N4O4/c1-37-25-14-13-20(28(38-2)29(25)39-3)19-32-17-8-18-34(23-11-6-4-9-21(23)30)26-15-16-27(36)35(33-26)24-12-7-5-10-22(24)31/h4-7,9-16,32H,8,17-19H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	7.0	30
Merck Research Laboratories					Assay Description The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...				Bioorg Med Chem Lett 16: 5809-13 (2006) Article DOI: 10.1016/j.bmcl.2006.08.074 BindingDB Entry DOI: 10.7270/Q28P5XSC
					More data for this Ligand-Target Pair