BDBM165336 US9062043, Table 13, Compound 2::US9062043, Table 20b, Compound 2

SMILES: CN(C)CCNc1nc2cc(ccc2c2cnccc12)C(O)=O

InChI Key: InChIKey=UTTHZOMQMFDLBQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 165336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165336 (US9062043, Table 13, Compound 2 | US9062043, Table...) Show SMILES CN(C)CCNc1nc2cc(ccc2c2cnccc12)C(O)=O Show InChI InChI=1S/C17H18N4O2/c1-21(2)8-7-19-16-13-5-6-18-10-14(13)12-4-3-11(17(22)23)9-15(12)20-16/h3-6,9-10H,7-8H2,1-2H3,(H,19,20)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165336 (US9062043, Table 13, Compound 2 | US9062043, Table...) Show SMILES CN(C)CCNc1nc2cc(ccc2c2cnccc12)C(O)=O Show InChI InChI=1S/C17H18N4O2/c1-21(2)8-7-19-16-13-5-6-18-10-14(13)12-4-3-11(17(22)23)9-15(12)20-16/h3-6,9-10H,7-8H2,1-2H3,(H,19,20)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description The human leukemia Jurkat T-cell line was maintained in RPMI 1640 (Cambrex) supplemented with 10% fetal calf serum and 50 ng/ml Geutamycin. Before tr...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165336 (US9062043, Table 13, Compound 2 | US9062043, Table...) Show SMILES CN(C)CCNc1nc2cc(ccc2c2cnccc12)C(O)=O Show InChI InChI=1S/C17H18N4O2/c1-21(2)8-7-19-16-13-5-6-18-10-14(13)12-4-3-11(17(22)23)9-15(12)20-16/h3-6,9-10H,7-8H2,1-2H3,(H,19,20)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair