BDBM165387 US9062043, Table 13, Compound 55

SMILES: CNc1ncc2c3ccc(cc3nc(Nc3cccc(c3)C#C)c2n1)C(O)=O

InChI Key: InChIKey=GRDNJAWJGYCPFS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165387 (US9062043, Table 13, Compound 55) Show SMILES CNc1ncc2c3ccc(cc3nc(Nc3cccc(c3)C#C)c2n1)C(O)=O Show InChI InChI=1S/C21H15N5O2/c1-3-12-5-4-6-14(9-12)24-19-18-16(11-23-21(22-2)26-18)15-8-7-13(20(27)28)10-17(15)25-19/h1,4-11H,2H3,(H,24,25)(H,27,28)(H,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair