BDBM165388 US9062043, Table 13, Compound 56

SMILES: OC(=O)c1ccc2c(c1)nc(Nc1ccc(Cl)c(c1)C(F)(F)F)c1ccncc21

InChI Key: InChIKey=XOCLJWSWOBSAOV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165388 (US9062043, Table 13, Compound 56) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1ccc(Cl)c(c1)C(F)(F)F)c1ccncc21 Show InChI InChI=1S/C20H11ClF3N3O2/c21-16-4-2-11(8-15(16)20(22,23)24)26-18-13-5-6-25-9-14(13)12-3-1-10(19(28)29)7-17(12)27-18/h1-9H,(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair