BDBM165394 US9062043, Table 13, Compound 62

SMILES: Nc1ncc2c(n1)c(Nc1cccc(Cl)c1)nc1cc(ccc21)C(O)=O

InChI Key: InChIKey=GPAFJYDMDLWXAO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165394 (US9062043, Table 13, Compound 62) Show SMILES Nc1ncc2c(n1)c(Nc1cccc(Cl)c1)nc1cc(ccc21)C(O)=O Show InChI InChI=1S/C18H12ClN5O2/c19-10-2-1-3-11(7-10)22-16-15-13(8-21-18(20)24-15)12-5-4-9(17(25)26)6-14(12)23-16/h1-8H,(H,22,23)(H,25,26)(H2,20,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
					More data for this Ligand-Target Pair