BDBM165421 US9062043, Table 13, Compound 89

SMILES: OC(=O)c1ccc2c(c1)nc(Nc1cccc(c1)C(F)(F)F)c1ccncc21

InChI Key: InChIKey=VSPGYELOUHWHGS-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM165421 (US9062043, Table 13, Compound 89) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(c1)C(F)(F)F)c1ccncc21 Show InChI InChI=1S/C20H12F3N3O2/c21-20(22,23)12-2-1-3-13(9-12)25-18-15-6-7-24-10-16(15)14-5-4-11(19(27)28)8-17(14)26-18/h1-10H,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...				US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF
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