BDBM165675 US9067922, 9

SMILES: Fc1ccc(NS(=O)(=O)c2ccc(Oc3ccccc3Cl)c(c2)C#N)nc1

InChI Key: InChIKey=NGDNFNVVVQUQTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM165675 (US9067922, 9) Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3ccccc3Cl)c(c2)C#N)nc1 Show InChI InChI=1S/C18H11ClFN3O3S/c19-15-3-1-2-4-17(15)26-16-7-6-14(9-12(16)10-21)27(24,25)23-18-8-5-13(20)11-22-18/h1-9,11H,(H,22,23)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	208	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Limited US Patent					Assay Description Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...				US Patent US9067922 (2015) BindingDB Entry DOI: 10.7270/Q2VQ31F0
					More data for this Ligand-Target Pair