BDBM165682 US9067922, 16

SMILES: Fc1ccc(NS(=O)(=O)c2ccc(Oc3cccc(F)c3F)c(c2)C#N)nc1

InChI Key: InChIKey=QWYMDAUAQMDTMT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM165682 (US9067922, 16) Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3cccc(F)c3F)c(c2)C#N)nc1 Show InChI InChI=1S/C18H10F3N3O3S/c19-12-4-7-17(23-10-12)24-28(25,26)13-5-6-15(11(8-13)9-22)27-16-3-1-2-14(20)18(16)21/h1-8,10H,(H,23,24)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	218	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Limited US Patent					Assay Description Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...				US Patent US9067922 (2015) BindingDB Entry DOI: 10.7270/Q2VQ31F0
					More data for this Ligand-Target Pair