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SMILES: Clc1cc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ccncn2)ccc1C#N

InChI Key: InChIKey=IYUWZZQVCAHTOW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165752   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM165752
PNG
(US9067922, 87)
Show SMILES Clc1cc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ccncn2)ccc1C#N
Show InChI InChI=1S/C18H10ClN5O3S/c19-16-8-14(2-1-12(16)9-20)27-17-4-3-15(7-13(17)10-21)28(25,26)24-18-5-6-22-11-23-18/h1-8,11H,(H,22,23,24)
KEGG

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Similars
US Patent
n/an/a>7.67E+3n/an/an/an/a7.4n/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...

US Patent US9067922 (2015)


BindingDB Entry DOI: 10.7270/Q2VQ31F0
More data for this
Ligand-Target Pair