BDBM165808 US9067922, 143

SMILES: COc1cc(Cl)ccc1Oc1ccc(cc1C#N)S(=O)(=O)Nc1ccc(F)cn1

InChI Key: InChIKey=MRZGQDBTSORKNA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM165808 (US9067922, 143) Show SMILES COc1cc(Cl)ccc1Oc1ccc(cc1C#N)S(=O)(=O)Nc1ccc(F)cn1 Show InChI InChI=1S/C19H13ClFN3O4S/c1-27-18-9-13(20)2-5-17(18)28-16-6-4-15(8-12(16)10-22)29(25,26)24-19-7-3-14(21)11-23-19/h2-9,11H,1H3,(H,23,24)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	79	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Limited US Patent					Assay Description Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...				US Patent US9067922 (2015) BindingDB Entry DOI: 10.7270/Q2VQ31F0
					More data for this Ligand-Target Pair