BindingDB logo
myBDB logout

null

SMILES: COc1ccc(C)cc1Oc1ccc(cc1C#N)S(=O)(=O)Nc1ccc(F)cn1

InChI Key: InChIKey=FMFZYDKCQWTZRI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165820   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM165820
PNG
(US9067922, 155)
Show SMILES COc1ccc(C)cc1Oc1ccc(cc1C#N)S(=O)(=O)Nc1ccc(F)cn1
Show InChI InChI=1S/C20H16FN3O4S/c1-13-3-6-18(27-2)19(9-13)28-17-7-5-16(10-14(17)11-22)29(25,26)24-20-8-4-15(21)12-23-20/h3-10,12H,1-2H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 191n/an/an/an/a7.4n/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...

US Patent US9067922 (2015)


BindingDB Entry DOI: 10.7270/Q2VQ31F0
More data for this
Ligand-Target Pair