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SMILES: Clc1cccc(Oc2ccc(cc2)S(=O)(=O)Nc2cccnc2)c1C#N

InChI Key: InChIKey=HWOCTJAKUZMSSS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165880   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM165880
PNG
(US9067922, 219)
Show SMILES Clc1cccc(Oc2ccc(cc2)S(=O)(=O)Nc2cccnc2)c1C#N
Show InChI InChI=1S/C18H12ClN3O3S/c19-17-4-1-5-18(16(17)11-20)25-14-6-8-15(9-7-14)26(23,24)22-13-3-2-10-21-12-13/h1-10,12,22H
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Similars
US Patent
n/an/a>1.00E+4n/an/an/an/a7.4n/a



Pfizer Limited

US Patent


Assay Description
Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...

US Patent US9067922 (2015)


BindingDB Entry DOI: 10.7270/Q2VQ31F0
More data for this
Ligand-Target Pair