BDBM165900 US9067922, 241

SMILES: Fc1ccc(NS(=O)(=O)c2ccc(Oc3cc(Cl)c(C#N)c(Cl)c3)c(c2)C#N)nc1

InChI Key: InChIKey=WQYHUGYKFYDFNH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM165900 (US9067922, 241) Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(Oc3cc(Cl)c(C#N)c(Cl)c3)c(c2)C#N)nc1 Show InChI InChI=1S/C19H9Cl2FN4O3S/c20-16-6-13(7-17(21)15(16)9-24)29-18-3-2-14(5-11(18)8-23)30(27,28)26-19-4-1-12(22)10-25-19/h1-7,10H,(H,25,26)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Limited US Patent					Assay Description Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...				US Patent US9067922 (2015) BindingDB Entry DOI: 10.7270/Q2VQ31F0
					More data for this Ligand-Target Pair