BDBM165924 US10214524, Example 19::US9067931, 19
SMILES: O=C(N[C@H]1CN2CCC1CC2)c1cc2cccc(-c3ccc(cc3)N3CCOCC3)c2s1
InChI Key: InChIKey=YODBKWMQALJHED-QHCPKHFHSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM165924 (US10214524, Example 19 | US9067931, 19) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon... | US Patent US10214524 (2019) BindingDB Entry DOI: 10.7270/Q2JH3PF0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM165924 (US10214524, Example 19 | US9067931, 19) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 20 | -9.76 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t... | US Patent US9067931 (2015) BindingDB Entry DOI: 10.7270/Q2M907F1 | |||||||||||
More data for this Ligand-Target Pair |