BDBM166347 US9067949, 204

SMILES: Cc1cc(cc2c3CNCCc3oc12)S(=O)(=O)c1ccc2sccc2c1

InChI Key: InChIKey=JTTIDZZIULKCCG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 166347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM166347 (US9067949, 204) Show SMILES Cc1cc(cc2c3CNCCc3oc12)S(=O)(=O)c1ccc2sccc2c1 Show InChI InChI=1S/C20H17NO3S2/c1-12-8-15(10-16-17-11-21-6-4-18(17)24-20(12)16)26(22,23)14-2-3-19-13(9-14)5-7-25-19/h2-3,5,7-10,21H,4,6,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.230	-13.1	n/a	n/a	n/a	n/a	n/a	7.5	25
Albany Molecular Research, Inc. US Patent					Assay Description For binding analysis vs. the human receptor, samples were incubated in 50 mM Tris-HCl, pH 7.5, 5 mM MgCl2, 1 mM EDTA (4% DMSO final) with 10 nM [N-me...				US Patent US9067949 (2015) BindingDB Entry DOI: 10.7270/Q23777FB
					More data for this Ligand-Target Pair