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BDBM166628 (8-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine hydrochloride (5m)

SMILES: Cc1ccc(cc1)-c1nc2c(C)cccn2c1CN

InChI Key: InChIKey=GCXIPEHQTCANSC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 166628   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase-IV (DDP-4)


(Homo sapiens (Human))
BDBM166628
PNG
((8-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)me...)
Show SMILES Cc1ccc(cc1)-c1nc2c(C)cccn2c1CN
Show InChI InChI=1S/C16H17N3/c1-11-5-7-13(8-6-11)15-14(10-17)19-9-3-4-12(2)16(19)18-15/h3-9H,10,17H2,1-2H3
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Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



China Pharmaceutical University



Assay Description
The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t...


Chem Biol Drug Des 86: 849-56 (2015)


Article DOI: 10.1111/cbdd.12560
BindingDB Entry DOI: 10.7270/Q2FJ2FJG
More data for this
Ligand-Target Pair