BDBM166628 (8-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine hydrochloride (5m)
SMILES: Cc1ccc(cc1)-c1nc2c(C)cccn2c1CN
InChI Key: InChIKey=GCXIPEHQTCANSC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Dipeptidyl peptidase-IV (DDP-4) (Homo sapiens (Human)) | BDBM166628 ((8-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)me...) | PDB B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University | Assay Description The DPP-4 Drug Discovery Kit (Enzo Life Sciences International, Inc.) was used for the assay of inhibition of DPP-4 activity. The assay is based on t... | Chem Biol Drug Des 86: 849-56 (2015) Article DOI: 10.1111/cbdd.12560 BindingDB Entry DOI: 10.7270/Q2FJ2FJG | |||||||||||
More data for this Ligand-Target Pair |