BDBM166673 3-(5-chloro-2,4-dihydroxyphenyl)-5,6-dihydrobenzo[d]isoxazol-7(4H)-one (13)

SMILES: Oc1cc(O)c(cc1Cl)-c1noc2c1CCCC2=O

InChI Key: InChIKey=FCBGFARIOASHLI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 166673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat-shock protein 90 (Hsp90) (Homo sapiens (Human))	BDBM166673 (3-(5-chloro-2,4-dihydroxyphenyl)-5,6-dihydrobenzo[...) Show SMILES Oc1cc(O)c(cc1Cl)-c1noc2c1CCCC2=O Show InChI InChI=1S/C13H10ClNO4/c14-8-4-7(10(17)5-11(8)18)12-6-2-1-3-9(16)13(6)19-15-12/h4-5,17-18H,1-3H2	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Milano					Assay Description The fluorescence polarization (FP) assay was performed as described in the reference (Bioorg Med Chem. 2010. 18:6031-6043).				Chem Biol Drug Des 86: 1030-5 (2015) Article DOI: 10.1111/cbdd.12570 BindingDB Entry DOI: 10.7270/Q22806CD
					More data for this Ligand-Target Pair